Rafael TREVISAN
Écotoxicologie et biochimie environnementale
Post-doctorant
Ifremer
Affectation
Laboratoire LEMAR
Panorama
Contact
Liens
Abstract – Signatures of licit and illicit drugs in marine plastics: connecting anthropogenic activities and ocean health through coastal plastic litter. In: GDR ‘Polymères & Océans’ 2025, Bordeaux.
Thématique de recherche : Mes recherches visent à déterminer si les espèces côtières telles que l’huître Crassostrea gigas peuvent résister aux multiples défis de la pollution plastique et du changement climatique attendus d’ici 2100, en mettant l’accent sur la biologie mitochondriale et le développement animal.
Parcours antérieur : I am an ecotoxicologist who studies the interplay between our environment and aquatic organisms such as mussels and fish. I received my BSc in Biological Sciences (2008), MSc in Biochemistry (2010), and PhD in Biochemistry (2014) from the Federal University of Santa Catarina (Brazil), with internships at the University of Plymouth (United Kingdom) and University College Cork (Ireland). I subsequently worked as a Postdoctoral Researcher at the Federal University of Santa Catarina (2014-2016), Duke University (US, 2016-2020), and Ifremer (France, 2022). I was also a Biochemistry adjunct professor at the Federal University of Santa Catarina (2020-2022). Beginning in 2023, I began a postdoctoral position at Université de Bretagne Occidentale and LEMAR.
Publications dans des revues à comité de lecture répertoriées dans les bases internationales
(ACL) depuis 2010
355235
ACL
trevisan
1
apa
50
default
desc
1
Trevisan, R.
201482
https://www-iuem.univ-brest.fr/lemar/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22R4QEBSEG%22%2C%22library%22%3A%7B%22id%22%3A355235%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Trevisan%20et%20al.%22%2C%22parsedDate%22%3A%222025-01-01%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3B%26lt%3Bstrong%26gt%3BTrevisan%2C%20R.%26lt%3B%5C%2Fstrong%26gt%3B%2C%20Trimpey-Warhaftig%2C%20R.%2C%20Gaston%2C%20K.%2C%20Butron%2C%20L.%2C%20Gaballah%2C%20S.%2C%20%26amp%3B%20Di%20Giulio%2C%20R.%20T.%20%282025%29.%20Polystyrene%20nanoplastics%20impact%20the%20bioenergetics%20of%20developing%20zebrafish%20and%20limit%20molecular%20and%20physiological%20adaptive%20responses%20to%20acute%20temperature%20stress.%20%26lt%3Bi%26gt%3BScience%20of%20The%20Total%20Environment%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B958%26lt%3B%5C%2Fi%26gt%3B%2C%20178026.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.scitotenv.2024.178026%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.scitotenv.2024.178026%26lt%3B%5C%2Fa%26gt%3B%20%26lt%3Ba%20title%3D%26%23039%3BCite%20in%20RIS%20Format%26%23039%3B%20class%3D%26%23039%3Bzp-CiteRIS%26%23039%3B%20data-zp-cite%3D%26%23039%3Bapi_user_id%3D355235%26amp%3Bitem_key%3DR4QEBSEG%26%23039%3B%20href%3D%26%23039%3Bjavascript%3Avoid%280%29%3B%26%23039%3B%26gt%3BCite%26lt%3B%5C%2Fa%26gt%3B%20%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Polystyrene%20nanoplastics%20impact%20the%20bioenergetics%20of%20developing%20zebrafish%20and%20limit%20molecular%20and%20physiological%20adaptive%20responses%20to%20acute%20temperature%20stress%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rafael%22%2C%22lastName%22%3A%22Trevisan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rose%22%2C%22lastName%22%3A%22Trimpey-Warhaftig%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kimberly%22%2C%22lastName%22%3A%22Gaston%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lynette%22%2C%22lastName%22%3A%22Butron%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Shaza%22%2C%22lastName%22%3A%22Gaballah%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Richard%20T.%22%2C%22lastName%22%3A%22Di%20Giulio%22%7D%5D%2C%22abstractNote%22%3A%22Plastic%20pollution%20is%20a%20growing%20environmental%20concern%20due%20to%20its%20ubiquitous%20impact%20on%20aquatic%20ecosystems.%20Nanoplastics%20can%20be%20generated%20from%20the%20breakdown%20of%20plastic%20waste%20and%20interact%20with%20organisms%20at%20the%20cellular%20level%2C%20potentially%20disrupting%20cellular%20physiology.%20We%20investigated%20the%20effects%20of%2044%5Cu00a0nm%20polystyrene%20nanoparticles%20%2844%5Cu00a0nm%20NanoPS%29%20on%20the%20development%20and%20physiology%20of%20zebrafish%20%28Danio%20rerio%29%20in%20the%20presence%20of%20sublethal%20heat%20stress%20%2832%5Cu00a0%5Cu00b0C%20vs%20control%2C%2028%5Cu00a0%5Cu00b0C%29.%20We%20hypothesized%20that%20the%20simultaneous%20exposure%20to%20nanoplastics%20and%20rising%20temperatures%20seriously%20threaten%20developing%20fish.%20This%20combination%20could%20create%20a%20critical%20imbalance%3A%20rising%20temperatures%20may%20lead%20to%20heightened%20energy%20demands%2C%20while%20nanoplastic%20exposure%20reduces%20energy%20production%2C%20threatening%20animal%20survival.%20As%20expected%2C%2032%5Cu00a0%5Cu00b0C%20increased%20markers%20associated%20with%20animal%20metabolism%20and%20developmental%20timing%2C%20such%20as%20growth%2C%20hatching%2C%20heart%20rate%2C%20and%20feeding.%20Changes%20in%20apoptosis%20dynamics%2C%20oxygen%20consumption%20rates%2C%20and%20a%20decrease%20in%20mitochondrial%20content%20were%20detected%20as%20adaptive%20processes%20to%20temperature.%2044%5Cu00a0nm%20NanoPS%20alone%20did%20not%20alter%20development%20but%20decreased%20mitochondrial%20efficiency%20in%20ATP%20production%20and%20increased%20apoptosis%20in%20the%20heart.%20Surprisingly%2C%20exposure%20to%2044%5Cu00a0nm%20NanoPS%20at%2032%5Cu00a0%5Cu00b0C%20did%20not%20cause%20major%20implications%20to%20survival%2C%20developmental%20success%2C%20or%20morphology.%20Still%2C%2044%5Cu00a0nm%20NanoPS%20mitigated%20the%20temperature-driven%20change%20in%20heart%20rate%2C%20increased%20oxidative%20stress%2C%20and%20decreased%20the%20coupling%20efficiency%20of%20the%20less%20abundant%20and%20highly%20active%20mitochondria%20under%20heat%20stress.%20We%20highlight%20the%20interplay%20between%20temperature%20and%20nanoplastics%20exposure%20and%20suggest%20that%20the%20combined%20impact%20of%20nanoplastics%20and%20temperature%20stress%20results%20in%20a%20scenario%20where%20physiological%20adaptations%20are%20strained%2C%20potentially%20leading%20to%20compromised%20development.%20This%20research%20underscores%20the%20need%20for%20further%20investigation%20into%20the%20metabolic%20costs%20of%20plastic%20pollution%2C%20particularly%20in%20the%20context%20of%20global%20warming%2C%20to%20better%20understand%20its%20long-term%20implications%20for%20aquatic%20life.%22%2C%22date%22%3A%222025-01-01%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.scitotenv.2024.178026%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.sciencedirect.com%5C%2Fscience%5C%2Farticle%5C%2Fpii%5C%2FS004896972408183X%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%220048-9697%22%2C%22language%22%3A%22%22%2C%22collections%22%3A%5B%22UTIXZUL6%22%5D%2C%22dateModified%22%3A%222026-01-19T13%3A17%3A28Z%22%7D%7D%2C%7B%22key%22%3A%22NPF8VSKP%22%2C%22library%22%3A%7B%22id%22%3A355235%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Trevisan%20et%20al.%22%2C%22parsedDate%22%3A%222026-02%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3B%26lt%3Bstrong%26gt%3BTrevisan%2C%20R.%26lt%3B%5C%2Fstrong%26gt%3B%2C%20Mello%2C%20D.%20F.%2C%20Le%20Gall%2C%20A.%2C%20Corporeau%2C%20C.%2C%20Fabioux%2C%20C.%2C%20Huvet%2C%20A.%2C%20%26amp%3B%20Paul-Pont%2C%20I.%20%282026%29.%20Each%20temperature%20degree%20counts%3A%20warming%20enhances%20polystyrene%20nanoplastic%20toxicity%20via%20metabolic%20disruption%20in%20a%20marine%20cellular%20model.%20%26lt%3Bi%26gt%3BAquatic%20Toxicology%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B291%26lt%3B%5C%2Fi%26gt%3B%2C%20107685.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.aquatox.2025.107685%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.aquatox.2025.107685%26lt%3B%5C%2Fa%26gt%3B%20%26lt%3Ba%20title%3D%26%23039%3BCite%20in%20RIS%20Format%26%23039%3B%20class%3D%26%23039%3Bzp-CiteRIS%26%23039%3B%20data-zp-cite%3D%26%23039%3Bapi_user_id%3D355235%26amp%3Bitem_key%3DNPF8VSKP%26%23039%3B%20href%3D%26%23039%3Bjavascript%3Avoid%280%29%3B%26%23039%3B%26gt%3BCite%26lt%3B%5C%2Fa%26gt%3B%20%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Each%20temperature%20degree%20counts%3A%20warming%20enhances%20polystyrene%20nanoplastic%20toxicity%20via%20metabolic%20disruption%20in%20a%20marine%20cellular%20model%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rafael%22%2C%22lastName%22%3A%22Trevisan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Danielle%20Ferraz%22%2C%22lastName%22%3A%22Mello%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Adele%22%2C%22lastName%22%3A%22Le%20Gall%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Charlotte%22%2C%22lastName%22%3A%22Corporeau%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Caroline%22%2C%22lastName%22%3A%22Fabioux%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Arnaud%22%2C%22lastName%22%3A%22Huvet%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ika%22%2C%22lastName%22%3A%22Paul-Pont%22%7D%5D%2C%22abstractNote%22%3A%22Climate%20change%20is%20significantly%20altering%20the%20thermal%20environment%20of%20marine%20species%2C%20causing%20shifts%20in%20animal%20metabolism%20through%20increased%20temperatures%20and%20more%20frequent%20marine%20heatwaves.%20These%20changes%20can%20impose%20additional%20physiological%20stress%20on%20coastal%20organisms%2C%20potentially%20worsening%20their%20sensitivity%20to%20environmental%20pollutants%20and%20metabolic%20disruptors%20such%20as%20plastics.%20Indeed%2C%20nanoplastics%20are%20concerning%20contaminants%20in%20marine%20ecosystems%2C%20with%20the%20potential%20to%20disrupt%20cellular%20metabolism%20and%20redox%20balance%20in%20aquatic%20organisms.%20This%20study%20examined%20if%20rising%20temperatures%20can%20influence%20the%20cellular%20toxicity%20of%20two%20model%20polystyrene%20nanoplastics%20%28nonfunctionalized%20Plain-NanoPS%20and%20amino-functionalized%20NH2-NanoPS%29%20in%20primary%20cultures%20of%20Pacific%20oyster%20Crassostrea%20gigas%20%28Magallana%20gigas%29%20hemocytes.%20We%20exposed%20hemocytes%20to%20a%20range%20of%20nanoplastic%20concentrations%20%280.1%20to%2010%20mg%5C%2FL%29%20at%20controlled%20temperatures%20from%2016%20degrees%20C%20to%2028%20degrees%20C%20and%20evaluated%20cellular%20responses%20using%20metabolic%2C%20oxidative%2C%20and%20viability%20biomarkers.%20This%20range%20of%20concentrations%20and%20temperatures%20reflects%20the%20NPs%20content%20in%20tissues%20and%20fluids%2C%20as%20well%20as%20temperature%20fluctuations%20in%20aquaculture%20sites%20and%20intertidal%20environments.%20Plain-NanoPS%20had%20minimal%20effects%2C%20while%20NH2-NanoPS%20caused%20temperature-dependent%20toxicity%2C%20impairing%20ATP%20production%2C%20reducing%20metabolic%20activity%2C%20and%20increasing%20reactive%20oxygen%20species%20levels.%20Integrated%20cellular%20biomarker%20analysis%20showed%20a%20shift%20from%20an%20adaptive%20to%20a%20stress-dominated%20metabolic%20phenotype%20under%20combined%20NH2-NanoPS%20exposure%20and%20warming%20conditions.%20Since%20both%20particle%20types%20exhibited%20similar%20surface%20charges%20in%20cell%20culture%20medium%2C%20factors%20other%20than%20surface%20charge%20might%20influence%20cellular%20toxicity.%20This%20research%20demonstrates%20that%20warming%20increases%20the%20metabolic%20toxicity%20of%20nanoplastics%20and%20can%20reduce%20the%20thermal%20resilience%20of%20oyster%20cells%20in%20vitro.%22%2C%22date%22%3A%22FEB%202026%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.aquatox.2025.107685%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.webofscience.com%5C%2Fapi%5C%2Fgateway%3FGWVersion%3D2%26SrcAuth%3DGetFTR%26SrcApp%3DWOS%26DestURL%3Dhttps%253A%252F%252Fct.prod.getft.io%252FY2xhcml2YXRlLGVsc2V2aWVyLE1UQXVNVEF4Tmk5cUxtRnhkV0YwYjNndU1qQXlOUzR4TURjMk9EVSxaV1l3T0dabFlURXRZakptT1MwME5USTVMVGczWm1ZdFpqTmpZelpqWmpCaVlXRTQsaHR0cHM6Ly93d3cuc2NpZW5jZWRpcmVjdC5jb20vc2NpZW5jZS9hcnRpY2xlL3BpaS9TMDE2NjQ0NVgyNTAwNDQ5Nz9wZXM9dm9y.jbLYNjuP3tXpxR5Nggit5wDfP_MBm-EQ-r7SD1s6DB8%26DestApp%3DGetFTR%26SrcItemId%3DWOS%3A001648224700001%26SrcAppSID%3DEUW1ED0A07Md0Qg4Dsc27WECOdNmy%26HMAC%3DvEzE244x%252Bp5xFxznLQinR1tmOYLhs82ANBQew%252F1uU%252BE%253D%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%220166-445X%2C%201879-1514%22%2C%22language%22%3A%22English%22%2C%22collections%22%3A%5B%22QICW69BQ%22%5D%2C%22dateModified%22%3A%222026-01-09T15%3A11%3A55Z%22%7D%7D%2C%7B%22key%22%3A%22FP8R93P9%22%2C%22library%22%3A%7B%22id%22%3A355235%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A10525%2C%22username%22%3A%22ltdm%22%2C%22name%22%3A%22Luis%20Tito%20de%20Morais%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fltdm%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Penha%20et%20al.%22%2C%22parsedDate%22%3A%222025-10-15%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BPenha%2C%20L.%20cristine%20de%20carvalho%2C%20Hennig%2C%20T.%20B.%2C%20Nogueira%2C%20D.%20J.%2C%20Pilotto%2C%20M.%20rangel%2C%20Matias%2C%20W.%20gerson%2C%20Dafre%2C%20A.%20luiz%2C%20%26amp%3B%20%26lt%3Bstrong%26gt%3BTrevisan%2C%20R.%26lt%3B%5C%2Fstrong%26gt%3B%20%282025%29.%20Cytotoxicity%20of%20polystyrene%20nanoplastics%20involves%20mitochondrial%20dysfunction%20and%20DNA%20damage%20in%20hemocytes%20of%20the%20Pacific%20oyster.%20%26lt%3Bi%26gt%3BEcotoxicology%20and%20Environmental%20Safety%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B305%26lt%3B%5C%2Fi%26gt%3B%2C%20119245.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.ecoenv.2025.119245%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.ecoenv.2025.119245%26lt%3B%5C%2Fa%26gt%3B%20%26lt%3Ba%20title%3D%26%23039%3BCite%20in%20RIS%20Format%26%23039%3B%20class%3D%26%23039%3Bzp-CiteRIS%26%23039%3B%20data-zp-cite%3D%26%23039%3Bapi_user_id%3D355235%26amp%3Bitem_key%3DFP8R93P9%26%23039%3B%20href%3D%26%23039%3Bjavascript%3Avoid%280%29%3B%26%23039%3B%26gt%3BCite%26lt%3B%5C%2Fa%26gt%3B%20%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Cytotoxicity%20of%20polystyrene%20nanoplastics%20involves%20mitochondrial%20dysfunction%20and%20DNA%20damage%20in%20hemocytes%20of%20the%20Pacific%20oyster%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Larissa%20cristine%20de%20carvalho%22%2C%22lastName%22%3A%22Penha%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thuanne%20Braulio%22%2C%22lastName%22%3A%22Hennig%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Diego%20Jose%22%2C%22lastName%22%3A%22Nogueira%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mariana%20rangel%22%2C%22lastName%22%3A%22Pilotto%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22William%20gerson%22%2C%22lastName%22%3A%22Matias%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alcir%20luiz%22%2C%22lastName%22%3A%22Dafre%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rafael%22%2C%22lastName%22%3A%22Trevisan%22%7D%5D%2C%22abstractNote%22%3A%22Nanoplastics%20represent%20an%20increasing%20ecological%20threat%20to%20marine%20ecosystems%2C%20with%20the%20potential%20to%20disrupt%20immune%20responses%2C%20oxidative%20stress%20pathways%2C%20and%20bioenergetics.%20We%20employed%20an%20in%20vitro%20cellular%20bioassay%20to%20investigate%20the%20distribution%2C%20metabolic%20disruption%2C%20and%20genotoxicity%20resulting%20from%2024%20h%20of%20exposure%20to%20polystyrene%20nanoplastics%20%28NanoPS%2C%20approximately%2090%20nm%29%20in%20the%20hemocytes%20of%20the%20Pacific%20oyster%20%28Crassostrea%20gigas%29.%20Transmission%20electron%20microscopy%20suggested%20the%20internalization%20and%20distribution%20of%20NanoPS%20within%20vesicles%2C%20the%20cytosol%2C%20and%20the%20nuclei%20of%20exposed%20hemocytes.%20Cytotoxicity%20assays%20revealed%20that%20metabolic%20activity%20%28resazurin%20assay%2C%20LC50%20%3D%2091.6%20mg%5C%2FL%29%20was%20more%20sensitive%20than%20lysosomal%20integrity%20%28neutral%20red%20assay%2C%20LC50%20%3D%20252.3%20mg%5C%2FL%29.%20Exposure%20to%20NanoPS%20also%20increased%20the%20levels%20of%20reactive%20oxygen%20species%20and%20DNA%20damage%20as%20low%20as%201.2%20mg%5C%2FL.%20Metabolic%20assays%20revealed%20that%20enhancing%20mitochondrial%20metabolism%20through%20galactose%20supplementation%20increased%20the%20cytotoxicity%20and%20DNA%20damage%20caused%20by%20NanoPS.%20Conversely%2C%20promoting%20anaerobic%20metabolism%20with%20glucose%20supplementation%20reduced%20these%20effects.%20Co-exposures%20with%20the%20mitochondrial%20uncoupler%20FCCP%20did%20not%20decrease%20cellular%20viability%20but%20elevated%20DNA%20damage.%20We%20suggest%20that%20mitochondria%20are%20a%20sensitive%20target%20of%20nanoplastics%20in%20bivalve%20hemocytes%2C%20highlighting%20the%20importance%20of%20considering%20aerobic%20metabolism%20in%20assessing%20nanoplastic%20toxicity.%20The%20strong%20correlation%20with%20the%20published%20in%20vivo%20effects%20of%20this%20same%20NanoPS%20highlights%20the%20biological%20relevance%20of%20this%20cellular%20toxicity%20assessment.%20This%20research%20supports%20the%20use%20of%20hemocyte-based%20cellular%20assays%20to%20complement%20in%20vivo%20studies%20for%20characterizing%20nanoplastic%20toxicity%20mechanisms%20in%20marine%20organisms.%22%2C%22date%22%3A%22OCT%2015%202025%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.ecoenv.2025.119245%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.webofscience.com%5C%2Fapi%5C%2Fgateway%3FGWVersion%3D2%26SrcAuth%3DGetFTR%26SrcApp%3DWOS%26DestURL%3Dhttps%253A%252F%252Fct.prod.getft.io%252FY2xhcml2YXRlLGVsc2V2aWVyLGh0dHBzOi8vd3d3LnNjaWVuY2VkaXJlY3QuY29tL3NjaWVuY2UvYXJ0aWNsZS9waWkvUzAxNDc2NTEzMjUwMTU5MDg_cGVzPXZvcg.vgIOm-PjRWXUO4HM-og6h0m9mEV3TDFGtFoJziTFsK0%26DestApp%3DGetFTR%26SrcItemId%3DWOS%3A001604657900001%26SrcAppSID%3DEUW1ED0F376Hh9HFbUbDgUm9dOIUW%26HMAC%3DRNrdvrAl60K%252BxsxLMpIgwhi%252BI853BCynXEGw9u%252Bg2DY%253D%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%220147-6513%2C%201090-2414%22%2C%22language%22%3A%22English%22%2C%22collections%22%3A%5B%22UTIXZUL6%22%5D%2C%22dateModified%22%3A%222025-11-20T17%3A04%3A15Z%22%7D%7D%2C%7B%22key%22%3A%226YT97QH9%22%2C%22library%22%3A%7B%22id%22%3A355235%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A10525%2C%22username%22%3A%22ltdm%22%2C%22name%22%3A%22Luis%20Tito%20de%20Morais%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fltdm%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Carrothers%20et%20al.%22%2C%22parsedDate%22%3A%222025-01-24%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BCarrothers%2C%20S.%2C%20%26lt%3Bstrong%26gt%3BTrevisan%2C%20R.%26lt%3B%5C%2Fstrong%26gt%3B%2C%20Jayasundara%2C%20N.%2C%20Pelletier%2C%20N.%2C%20Weeks%2C%20E.%2C%20Meyer%2C%20J.%20N.%2C%20Di%20Giulio%2C%20R.%2C%20%26amp%3B%20Weinhouse%2C%20C.%20%282025%29.%20An%20epigenetic%20memory%20at%20the%20%26lt%3Bi%26gt%3BCYP1A%26lt%3B%5C%2Fi%26gt%3B%20gene%20in%20cancer-resistant%2C%20pollution-adapted%20killifish.%20%26lt%3Bi%26gt%3BSCIENTIFIC%20REPORTS%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B15%26lt%3B%5C%2Fi%26gt%3B%281%29%2C%203033.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41598-024-82740-w%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41598-024-82740-w%26lt%3B%5C%2Fa%26gt%3B%20%26lt%3Ba%20title%3D%26%23039%3BCite%20in%20RIS%20Format%26%23039%3B%20class%3D%26%23039%3Bzp-CiteRIS%26%23039%3B%20data-zp-cite%3D%26%23039%3Bapi_user_id%3D355235%26amp%3Bitem_key%3D6YT97QH9%26%23039%3B%20href%3D%26%23039%3Bjavascript%3Avoid%280%29%3B%26%23039%3B%26gt%3BCite%26lt%3B%5C%2Fa%26gt%3B%20%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22An%20epigenetic%20memory%20at%20the%20%3Ci%3ECYP1A%3C%5C%2Fi%3E%20gene%20in%20cancer-resistant%2C%20pollution-adapted%20killifish%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Samantha%22%2C%22lastName%22%3A%22Carrothers%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rafael%22%2C%22lastName%22%3A%22Trevisan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nishad%22%2C%22lastName%22%3A%22Jayasundara%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nicole%22%2C%22lastName%22%3A%22Pelletier%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Emma%22%2C%22lastName%22%3A%22Weeks%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joel%20N.%22%2C%22lastName%22%3A%22Meyer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Richard%22%2C%22lastName%22%3A%22Di%20Giulio%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Caren%22%2C%22lastName%22%3A%22Weinhouse%22%7D%5D%2C%22abstractNote%22%3A%22Human%20exposure%20to%20polycyclic%20aromatic%20hydrocarbons%20%28PAH%29%20is%20a%20significant%20public%20health%20problem%20that%20will%20worsen%20with%20a%20warming%20climate%20and%20increased%20large-scale%20wildfires.%20Here%2C%20we%20characterize%20an%20epigenetic%20memory%20at%20the%20cytochrome%20P450%201%20A%20%28CYP1A%29%20gene%20in%20wild%20Fundulus%20heteroclitus%20that%20have%20adapted%20to%20chronic%2C%20extreme%20PAH%20pollution.%20In%20wild-type%20fish%2C%20CYP1A%20is%20highly%20induced%20by%20PAH.%20In%20PAH-tolerant%20fish%2C%20CYP1A%20induction%20is%20blunted.%20Since%20CYP1A%20metabolically%20activates%20PAH%2C%20this%20memory%20protects%20these%20fish%20from%20PAH-mediated%20cancer.%20However%2C%20PAH-tolerant%20fish%20reared%20in%20clean%20water%20recover%20CYP1A%20inducibility%2C%20indicating%20a%20non-genetic%20effect.%20We%20observed%20epigenetic%20control%20of%20this%20reversible%20memory%20of%20generational%20PAH%20stress%20in%20F1%20PAH-tolerant%20embryos.%20We%20detected%20a%20bivalent%20domain%20in%20the%20CYP1A%20promoter%20enhancer%20comprising%20both%20activating%20and%20repressive%20histone%20post-translational%20modifications.%20Activating%20modifications%2C%20relative%20to%20repressive%20ones%2C%20showed%20greater%20increases%20in%20response%20to%20PAH%20in%20sensitive%20embryos%2C%20relative%20to%20tolerant%2C%20consistent%20with%20greater%20gene%20activation.%20PAH-tolerant%20adult%20fish%20showed%20persistent%20induction%20of%20CYP1A%20long%20after%20exposure%20cessation%2C%20which%20is%20consistent%20with%20defective%20CYP1A%20shutoff.%20These%20results%20indicate%20that%20PAH-tolerant%20fish%20have%20epigenetic%20protection%20against%20PAH-induced%20cancer%20in%20early%20life%20that%20degrades%20in%20response%20to%20continuous%20gene%20activation.%22%2C%22date%22%3A%22JAN%2024%202025%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41598-024-82740-w%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.webofscience.com%5C%2Fapi%5C%2Fgateway%3FGWVersion%3D2%26SrcAuth%3DPQPLP%26SrcApp%3DWOS%26DestURL%3Dhttps%253A%252F%252Fwww.proquest.com%252Fdocview%252F3159561942%252Fembedded%252FM5R06SWUZXPLKYT8%253Fpq-origsite%253Dwos%26DestApp%3DPQP_ExternalLink%26SrcItemId%3DWOS%3A001406378400025%26SrcAppSID%3DEUW1ED0DB9ZfHB2Rq8qcujaBWvePz%26HMAC%3DLb8UZV3Tvn%252BZL3wryZ2P1So%252FwWBJSUbdvAjHyiMpaf4%253D%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%222045-2322%22%2C%22language%22%3A%22English%22%2C%22collections%22%3A%5B%22UTIXZUL6%22%5D%2C%22dateModified%22%3A%222025-05-08T07%3A42%3A48Z%22%7D%7D%2C%7B%22key%22%3A%22JUKI9LBV%22%2C%22library%22%3A%7B%22id%22%3A355235%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A10525%2C%22username%22%3A%22ltdm%22%2C%22name%22%3A%22Luis%20Tito%20de%20Morais%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fltdm%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Gabe%20et%20al.%22%2C%22parsedDate%22%3A%222025-03%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BGabe%2C%20H.%20B.%2C%20Taruhn%2C%20K.%20A.%2C%20Mello%2C%20D.%20F.%2C%20Lebrun%2C%20M.%2C%20Paillard%2C%20C.%2C%20Corporeau%2C%20C.%2C%20Dafre%2C%20A.%20L.%2C%20%26amp%3B%20%26lt%3Bstrong%26gt%3BTrevisan%2C%20R.%26lt%3B%5C%2Fstrong%26gt%3B%20%282025%29.%20Prolonged%20curcumin%20supplementation%20causes%20tissue-specific%20antioxidant%20responses%20in%20adult%20oysters%3A%20Potential%20implications%20for%20resilience%20against%20abiotic%20and%20biotic%20stressors%20in%20the%20aquaculture%20industry.%20%26lt%3Bi%26gt%3BAQUATIC%20TOXICOLOGY%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B280%26lt%3B%5C%2Fi%26gt%3B%2C%20107282.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.aquatox.2025.107282%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.aquatox.2025.107282%26lt%3B%5C%2Fa%26gt%3B%20%26lt%3Ba%20title%3D%26%23039%3BCite%20in%20RIS%20Format%26%23039%3B%20class%3D%26%23039%3Bzp-CiteRIS%26%23039%3B%20data-zp-cite%3D%26%23039%3Bapi_user_id%3D355235%26amp%3Bitem_key%3DJUKI9LBV%26%23039%3B%20href%3D%26%23039%3Bjavascript%3Avoid%280%29%3B%26%23039%3B%26gt%3BCite%26lt%3B%5C%2Fa%26gt%3B%20%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Prolonged%20curcumin%20supplementation%20causes%20tissue-specific%20antioxidant%20responses%20in%20adult%20oysters%3A%20Potential%20implications%20for%20resilience%20against%20abiotic%20and%20biotic%20stressors%20in%20the%20aquaculture%20industry%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Heloisa%20Barbara%22%2C%22lastName%22%3A%22Gabe%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Karine%20Amabile%22%2C%22lastName%22%3A%22Taruhn%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Danielle%20Ferraz%22%2C%22lastName%22%3A%22Mello%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Melody%22%2C%22lastName%22%3A%22Lebrun%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christine%22%2C%22lastName%22%3A%22Paillard%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Charlotte%22%2C%22lastName%22%3A%22Corporeau%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alcir%20Luiz%22%2C%22lastName%22%3A%22Dafre%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rafael%22%2C%22lastName%22%3A%22Trevisan%22%7D%5D%2C%22abstractNote%22%3A%22Aquatic%20animals%20inhabiting%20marine%20coastal%20environments%20are%20highly%20susceptible%20to%20environmental%20fluctuations%20and%20pollution%2C%20exemplified%20by%20widespread%20mass%20mortalities%20induced%20by%20marine%20bacteria%20or%20viruses.%20Enhancing%20antioxidant%20defenses%20presents%20a%20promising%20strategy%20to%20mitigate%20such%20environmental%20stressors.%20We%20postulated%20that%20supplementation%20of%20oysters%20with%20natural%20compounds%20such%20as%20flavonoids%2C%20exemplified%20by%20curcumin%20%28CUR%29%2C%20could%20effectively%20bolster%20their%20antioxidant%20protection.%20Adult%20Pacific%20oysters%20were%20supplemented%20with%20CUR%20%2830%20mu%20M%29%20in%20seawater%20for%202%2C%204%2C%208%2C%20and%2016%20days.%20CUR%20metabolites%20progressively%20accumulated%20in%20gills%2C%20mantle%2C%20and%20digestive%20glands.%20Notably%2C%20oyster%20antioxidant%20response%20was%20significantly%20augmented%2C%20as%20evidenced%20by%20elevated%20glutathione%20%28GSH%29%20levels%2C%20and%20enhanced%20activities%20of%20glutathione%20reductase%20%28GR%29%2C%20thioredoxin%20reductase%20%28TrxR%29%2C%20and%20glutathione%20S-transferase%20%28GST%29%20after%204%2C%208%2C%20and%2016%20days%20of%20CUR%20supplementation.%20This%20response%20was%20tissue-specific%2C%20with%20the%20most%20pronounced%20increase%20in%20gills%2C%20followed%20by%20mantle%2C%20whereas%20digestive%20gland%20exhibited%20minimal%20response.%20After%20being%20supplemented%20with%20CUR%20for%208%20days%2C%20oysters%20were%20subjected%20to%20antioxidant-disrupting%20agents%20such%20as%20N-ethylmaleimide%20%28NEM%29%2C%201-chloro-2%2C4-dinitrobenzene%20%28CDNB%29.%20Both%20chemicals%20reduced%20antioxidant%20protection%20in%20untreated%20animals.%20However%2C%20CUR%20supplementation%20prevented%20these%20redox-disrupting%20effects%2C%20suggesting%20the%20potential%20ability%20of%20CUR%20to%20counteract%20antioxidant%20stressors.%20The%20effects%20of%208%20days%20of%20CUR%20supplementation%20were%20also%20tested%20against%20the%20lethal%20effects%20of%20the%20pathogens%20V.%20tapetis%2C%20V%2C%20alginolyticus%2C%20and%20V.%20anguillarum%2C%20but%20CUR%20failed%20to%20induce%20immunological%20protection.%20The%20antioxidant%20protection%20induced%20by%20CUR%20holds%20promise%20for%20application%20in%20aquaculture%20to%20bolster%20animal%20health%20and%20resilience%20against%20abiotic%20stressors.%20Further%20research%20is%20needed%20to%20investigate%20the%20long-term%20impact%20of%20CUR%20supplementation%20and%20its%20role%20against%20biotic%20stressors%2C%20such%20as%20bacterial%20and%20viral%20infections.%22%2C%22date%22%3A%22MAR%202025%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.aquatox.2025.107282%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.webofscience.com%5C%2Fwos%5C%2Fwoscc%5C%2Ffull-record%5C%2FWOS%3A001428451200001%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%220166-445X%2C%201879-1514%22%2C%22language%22%3A%22English%22%2C%22collections%22%3A%5B%22UTIXZUL6%22%5D%2C%22dateModified%22%3A%222025-03-06T07%3A53%3A38Z%22%7D%7D%2C%7B%22key%22%3A%22SLPQRST5%22%2C%22library%22%3A%7B%22id%22%3A355235%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A10525%2C%22username%22%3A%22ltdm%22%2C%22name%22%3A%22Luis%20Tito%20de%20Morais%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fltdm%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Gabe%20et%20al.%22%2C%22parsedDate%22%3A%222025-02%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BGabe%2C%20H.%20B.%2C%20Queiroga%2C%20F.%20R.%2C%20Taruhn%2C%20K.%20A.%2C%20%26amp%3B%20%26lt%3Bstrong%26gt%3BTrevisan%2C%20R.%26lt%3B%5C%2Fstrong%26gt%3B%20%282025%29.%20Mitigating%20oxidative%20stress%20in%20oyster%20larvae%3A%20Curcumin%20promotes%20enhanced%20redox%20balance%2C%20antioxidant%20capacity%2C%20development%2C%20and%20resistance%20to%20antifouling%20compounds.%20%26lt%3Bi%26gt%3BAQUATIC%20TOXICOLOGY%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B279%26lt%3B%5C%2Fi%26gt%3B%2C%20107231.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.aquatox.2024.107231%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.aquatox.2024.107231%26lt%3B%5C%2Fa%26gt%3B%20%26lt%3Ba%20title%3D%26%23039%3BCite%20in%20RIS%20Format%26%23039%3B%20class%3D%26%23039%3Bzp-CiteRIS%26%23039%3B%20data-zp-cite%3D%26%23039%3Bapi_user_id%3D355235%26amp%3Bitem_key%3DSLPQRST5%26%23039%3B%20href%3D%26%23039%3Bjavascript%3Avoid%280%29%3B%26%23039%3B%26gt%3BCite%26lt%3B%5C%2Fa%26gt%3B%20%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Mitigating%20oxidative%20stress%20in%20oyster%20larvae%3A%20Curcumin%20promotes%20enhanced%20redox%20balance%2C%20antioxidant%20capacity%2C%20development%2C%20and%20resistance%20to%20antifouling%20compounds%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Heloisa%20Barbara%22%2C%22lastName%22%3A%22Gabe%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Fernando%20Ramos%22%2C%22lastName%22%3A%22Queiroga%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Karine%20Amabile%22%2C%22lastName%22%3A%22Taruhn%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rafael%22%2C%22lastName%22%3A%22Trevisan%22%7D%5D%2C%22abstractNote%22%3A%22Curcumin%20%28CUR%29%20is%20a%20natural%20compound%20recognized%20for%20stimulating%20the%20expression%20of%20antioxidant%20genes.%20This%20characteristic%20has%20been%20used%20to%20promote%20animal%20health%20and%20production%20in%20aquaculture%20settings.%20We%20hypothesized%20that%20supplementing%20embryos%20of%20Crassostrea%20gigas%20oysters%20with%20CUR%20would%20improve%20their%20antioxidant%20capacity%2C%20development%2C%20and%20resilience%20to%20stress.%20Embryos%20were%20exposed%20to%20CUR%20ranging%20from%200.03%20to%2030%20mu%20M%20for%2024%20h.%20Their%20development%20was%20assessed%2C%20along%20with%20measurements%20of%20glutathione%20levels%2C%20glutathione%20S-transferase%20activity%2C%20antioxidant%20capacity%2C%20production%20of%20reactive%20oxygen%20species%20%28ROS%29%2C%20metabolic%20activity%2C%20and%20resistance%20to%20organic%20hydroperoxide%20and%20the%20antifouling%20compound%20dichlorooctylisothiazolinone%20%28DCOIT%29.%20Low%20curcumin%20concentrations%20%28up%20to%201%20mu%20M%29%20activated%20the%20D-larvae%20antioxidant%20system%2C%20with%20a%20significant%20threefold%20increase%20in%20glutathione%20levels%20and%20a%2050%20%25%20decrease%20in%20ROS%20production.%20This%20enhancement%20in%20antioxidant%20defense%20improved%20the%20ability%20of%20larvae%20to%20detoxify%20organic%20hydroperoxide.%20It%20also%20resulted%20in%20larger%20larval%20size%20and%20increased%20survival%20rates%2C%20whether%20under%20normal%20conditions%20or%20exposure%20to%20peroxide%20or%20DCOIT.%20CUR%20shows%20great%20promise%20in%20supporting%20larval%20development%2C%20but%20high%20concentrations%20were%20toxic%20%28EC50%20%3D%202.90%20mu%20M%29%2C%20probably%20due%20to%20excessive%20antioxidant%20activation.%20Our%20results%20indicate%20that%20the%20antioxidant%20system%20may%20play%20a%20role%20in%20controlling%20bivalve%20early%20development.%20Understanding%20how%20antioxidants%20influence%20redox%20balance%20and%20gene%20expression%20during%20early%20life%20can%20enhance%20our%20knowledge%20of%20stress%20response%20mechanisms%20in%20marine%20organisms%2C%20offering%20insights%20into%20how%20they%20cope%20with%20pollutants%20and%20environmental%20challenges.%20Integrating%20CUR%20and%20antioxidant%20defense%20pathway%20approaches%20into%20aquaculture%20practices%20could%20boost%20productivity%20and%20sustainability%20in%20oyster%20aquaculture.%22%2C%22date%22%3A%22FEB%202025%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.aquatox.2024.107231%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.webofscience.com%5C%2Fwos%5C%2Fwoscc%5C%2Ffull-record%5C%2FWOS%3A001402447900001%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%220166-445X%2C%201879-1514%22%2C%22language%22%3A%22English%22%2C%22collections%22%3A%5B%22UTIXZUL6%22%5D%2C%22dateModified%22%3A%222025-02-01T13%3A01%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22YQRQJLTZ%22%2C%22library%22%3A%7B%22id%22%3A355235%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A10525%2C%22username%22%3A%22ltdm%22%2C%22name%22%3A%22Luis%20Tito%20de%20Morais%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fltdm%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Trevisan%20and%20Mello%22%2C%22parsedDate%22%3A%222024-01%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3B%26lt%3Bstrong%26gt%3BTrevisan%2C%20R.%26lt%3B%5C%2Fstrong%26gt%3B%2C%20%26amp%3B%20Mello%2C%20D.%20F.%20%282024%29.%20Redox%20control%20of%20antioxidants%2C%20metabolism%2C%20immunity%2C%20and%20development%20at%20the%20core%20of%20stress%20adaptation%20of%20the%20oyster%20Crassostrea%20gigas%20to%20the%20dynamic%20intertidal%20environment.%20%26lt%3Bi%26gt%3BFREE%20RADICAL%20BIOLOGY%20AND%20MEDICINE%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B210%26lt%3B%5C%2Fi%26gt%3B%2C%2085%26%23x2013%3B106.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.freeradbiomed.2023.11.003%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.freeradbiomed.2023.11.003%26lt%3B%5C%2Fa%26gt%3B%20%26lt%3Ba%20title%3D%26%23039%3BCite%20in%20RIS%20Format%26%23039%3B%20class%3D%26%23039%3Bzp-CiteRIS%26%23039%3B%20data-zp-cite%3D%26%23039%3Bapi_user_id%3D355235%26amp%3Bitem_key%3DYQRQJLTZ%26%23039%3B%20href%3D%26%23039%3Bjavascript%3Avoid%280%29%3B%26%23039%3B%26gt%3BCite%26lt%3B%5C%2Fa%26gt%3B%20%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Redox%20control%20of%20antioxidants%2C%20metabolism%2C%20immunity%2C%20and%20development%20at%20the%20core%20of%20stress%20adaptation%20of%20the%20oyster%20Crassostrea%20gigas%20to%20the%20dynamic%20intertidal%20environment%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rafael%22%2C%22lastName%22%3A%22Trevisan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Danielle%20F.%22%2C%22lastName%22%3A%22Mello%22%7D%5D%2C%22abstractNote%22%3A%22This%20review%20uses%20the%20marine%20bivalve%20Crassostrea%20gigas%20to%20highlight%20redox%20reactions%20and%20control%20systems%20in%20species%20living%20in%20dynamic%20intertidal%20environments.%20Intertidal%20species%20face%20daily%20and%20seasonal%20environmental%20variability%2C%20including%20temperature%2C%20oxygen%2C%20salinity%2C%20and%20nutritional%20changes.%20Increasing%20anthropogenic%20pressure%20can%20bring%20pollutants%20and%20pathogens%20as%20additional%20stressors.%20Surprisingly%2C%20C.%20gigas%20demonstrates%20impressive%20adaptability%20to%20most%20of%20these%20challenges.%20We%20explore%20how%20ROS%20production%2C%20antioxidant%20protection%2C%20redox%20signaling%2C%20and%20metabolic%20adjustments%20can%20shed%20light%20on%20how%20redox%20biology%20supports%20oyster%20survival%20in%20harsh%20conditions.%20The%20review%20provides%20%28i%29%20a%20brief%20summary%20of%20shared%20redox%20sensing%20processes%20in%20metazoan%3B%20%28ii%29%20an%20overview%20of%20unique%20characteristics%20of%20the%20C.%20gigas%20intertidal%20habitat%20and%20the%20suitability%20of%20this%20species%20as%20a%20model%20organism%3B%20%28iii%29%20insights%20into%20the%20redox%20biology%20of%20C.%20gigas%2C%20including%20ROS%20sources%2C%20signaling%20pathways%2C%20ROS-scavenging%20systems%2C%20and%20thiolcontaining%20proteins%3B%20and%20examples%20of%20%28iv%29%20hot%20topics%20that%20are%20underdeveloped%20in%20bivalve%20research%20linking%20redox%20biology%20with%20immunometabolism%2C%20physioxia%2C%20and%20development.%20Given%20its%20plasticity%20to%20environmental%20changes%2C%20C.%20gigas%20is%20a%20valuable%20model%20for%20studying%20the%20role%20of%20redox%20biology%20in%20the%20adaptation%20to%20harsh%20habitats%2C%20potentially%20providing%20novel%20insights%20for%20basic%20and%20applied%20studies%20in%20marine%20and%20comparative%20biochemistry%20and%20physiology.%22%2C%22date%22%3A%22JAN%202024%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.freeradbiomed.2023.11.003%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.webofscience.com%5C%2Fwos%5C%2Fwoscc%5C%2Ffull-record%5C%2FWOS%3A001129025900001%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%220891-5849%2C%201873-4596%22%2C%22language%22%3A%22English%22%2C%22collections%22%3A%5B%22MXS8HMWQ%22%5D%2C%22dateModified%22%3A%222024-01-11T12%3A45%3A32Z%22%7D%7D%2C%7B%22key%22%3A%22ZCY4LVKR%22%2C%22library%22%3A%7B%22id%22%3A355235%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A10525%2C%22username%22%3A%22ltdm%22%2C%22name%22%3A%22Luis%20Tito%20de%20Morais%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fltdm%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Dupoue%20et%20al.%22%2C%22parsedDate%22%3A%222023-10%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BDupoue%2C%20A.%2C%20Mello%2C%20D.%20F.%2C%20%26lt%3Bstrong%26gt%3BTrevisan%2C%20R.%26lt%3B%5C%2Fstrong%26gt%3B%2C%20Dubreuil%2C%20C.%2C%20Queau%2C%20I.%2C%20Petton%2C%20S.%2C%20Huvet%2C%20A.%2C%20Guevel%2C%20B.%2C%20Com%2C%20E.%2C%20Pernet%2C%20F.%2C%20Salin%2C%20K.%2C%20Fleury%2C%20E.%2C%20%26amp%3B%20Corporeau%2C%20C.%20%282023%29.%20Intertidal%20limits%20shape%20covariation%20between%20metabolic%20plasticity%2C%20oxidative%20stress%20and%20telomere%20dynamics%20in%20Pacific%20oyster%26lt%3Bi%26gt%3B%20%28Crassostrea%26lt%3B%5C%2Fi%26gt%3B%26lt%3Bi%26gt%3B%20gigas%29%26lt%3B%5C%2Fi%26gt%3B.%20%26lt%3Bi%26gt%3BMARINE%20ENVIRONMENTAL%20RESEARCH%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B191%26lt%3B%5C%2Fi%26gt%3B%2C%20106149.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.marenvres.2023.106149%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.marenvres.2023.106149%26lt%3B%5C%2Fa%26gt%3B%20%26lt%3Ba%20title%3D%26%23039%3BCite%20in%20RIS%20Format%26%23039%3B%20class%3D%26%23039%3Bzp-CiteRIS%26%23039%3B%20data-zp-cite%3D%26%23039%3Bapi_user_id%3D355235%26amp%3Bitem_key%3DZCY4LVKR%26%23039%3B%20href%3D%26%23039%3Bjavascript%3Avoid%280%29%3B%26%23039%3B%26gt%3BCite%26lt%3B%5C%2Fa%26gt%3B%20%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Intertidal%20limits%20shape%20covariation%20between%20metabolic%20plasticity%2C%20oxidative%20stress%20and%20telomere%20dynamics%20in%20Pacific%20oyster%3Ci%3E%20%28Crassostrea%3C%5C%2Fi%3E%3Ci%3E%20gigas%29%3C%5C%2Fi%3E%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreaz%22%2C%22lastName%22%3A%22Dupoue%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Danielle%20Ferraz%22%2C%22lastName%22%3A%22Mello%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rafael%22%2C%22lastName%22%3A%22Trevisan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christine%22%2C%22lastName%22%3A%22Dubreuil%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Isabelle%22%2C%22lastName%22%3A%22Queau%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sebastien%22%2C%22lastName%22%3A%22Petton%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Arnaud%22%2C%22lastName%22%3A%22Huvet%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Blandine%22%2C%22lastName%22%3A%22Guevel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Emmanuelle%22%2C%22lastName%22%3A%22Com%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Fabrice%22%2C%22lastName%22%3A%22Pernet%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Karine%22%2C%22lastName%22%3A%22Salin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elodie%22%2C%22lastName%22%3A%22Fleury%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Charlotte%22%2C%22lastName%22%3A%22Corporeau%22%7D%5D%2C%22abstractNote%22%3A%22In%20intertidal%20zones%2C%20species%20such%20as%20sessile%20shellfish%20exhibit%20extended%20phenotypic%20plasticity%20to%20face%20rapid%20environmental%20changes%2C%20but%20whether%20frequent%20exposure%20to%20intertidal%20limits%20of%20the%20distribution%20range%20impose%20physiological%20costs%20for%20the%20animal%20remains%20elusive.%20Here%2C%20we%20explored%20how%20phenotypic%20plasticity%20varied%20along%20foreshore%20range%20at%20multiple%20organization%20levels%2C%20from%20molecular%20to%20cellular%20and%20whole%20organism%20acclimatization%2C%20in%20the%20Pacific%20oyster%20%28Crassostrea%20gigas%29.%20We%20exposed%207-month-old%20individuals%20for%20up%20to%2016%20months%20to%20three%20foreshore%20levels%20covering%20the%20vertical%20range%20for%20this%20species%2C%20representing%2020%2C%2050%20and%2080%25%20of%20the%20time%20spent%20submerged%20monthly.%20Individuals%20at%20the%20upper%20range%20limit%20produced%20energy%20more%20efficiently%2C%20as%20seen%20by%20steeper%20metabolic%20reactive%20norms%20and%20unaltered%20ATP%20levels%20despite%20reduced%20mitochondrial%20density.%20By%20spending%20most%20of%20their%20time%20emerged%2C%20oysters%20mounted%20an%20antioxidant%20shielding%20concomitant%20with%20lower%20levels%20of%20pro-oxidant%20proteins%20and%20postponed%20age-related%20telomere%20attrition.%20Instead%2C%20individuals%20exposed%20at%20the%20lower%20limit%20range%20near%20subtidal%20conditions%20showed%20lower%20energy%20efficiencies%2C%20greater%20oxidative%20stress%20and%20shorter%20telomere%20length.%20These%20results%20unraveled%20the%20extended%20acclimatization%20strategies%20and%20the%20physiological%20costs%20of%20living%20too%20fast%20in%20subtidal%20conditions%20for%20an%20intertidal%20species.%22%2C%22date%22%3A%22OCT%202023%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.marenvres.2023.106149%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.webofscience.com%5C%2Fwos%5C%2Fwoscc%5C%2Ffull-record%5C%2FWOS%3A001072189400001%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%220141-1136%2C%201879-0291%22%2C%22language%22%3A%22English%22%2C%22collections%22%3A%5B%22IMMDEEP2%22%5D%2C%22dateModified%22%3A%222023-10-21T10%3A14%3A48Z%22%7D%7D%2C%7B%22key%22%3A%225TXTQAHN%22%2C%22library%22%3A%7B%22id%22%3A355235%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A10525%2C%22username%22%3A%22ltdm%22%2C%22name%22%3A%22Luis%20Tito%20de%20Morais%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fltdm%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Trevisan%20et%20al.%22%2C%22parsedDate%22%3A%222022-12-07%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3B%26lt%3Bstrong%26gt%3BTrevisan%2C%20R.%26lt%3B%5C%2Fstrong%26gt%3B%2C%20Brander%2C%20S.%20M.%2C%20%26amp%3B%20Coffin%2C%20S.%20%282022%29.%20Editorial%3A%20Microplastics%20in%20water%20and%20potential%20impacts%20on%20human%20health.%20%26lt%3Bi%26gt%3BFrontiers%20in%20Water%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B4%26lt%3B%5C%2Fi%26gt%3B%2C%201101313.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3389%5C%2Ffrwa.2022.1101313%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3389%5C%2Ffrwa.2022.1101313%26lt%3B%5C%2Fa%26gt%3B%20%26lt%3Ba%20title%3D%26%23039%3BCite%20in%20RIS%20Format%26%23039%3B%20class%3D%26%23039%3Bzp-CiteRIS%26%23039%3B%20data-zp-cite%3D%26%23039%3Bapi_user_id%3D355235%26amp%3Bitem_key%3D5TXTQAHN%26%23039%3B%20href%3D%26%23039%3Bjavascript%3Avoid%280%29%3B%26%23039%3B%26gt%3BCite%26lt%3B%5C%2Fa%26gt%3B%20%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Editorial%3A%20Microplastics%20in%20water%20and%20potential%20impacts%20on%20human%20health%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rafael%22%2C%22lastName%22%3A%22Trevisan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Susanne%20M.%22%2C%22lastName%22%3A%22Brander%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Scott%22%2C%22lastName%22%3A%22Coffin%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%22DEC%207%202022%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.3389%5C%2Ffrwa.2022.1101313%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.webofscience.com%5C%2Fwos%5C%2Fwoscc%5C%2Fsummary%5C%2F8f92b190-4a98-40e7-a1a6-18362629beb2-6b5cc4d6%5C%2Frelevance%5C%2F1%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%22%22%2C%22language%22%3A%22English%22%2C%22collections%22%3A%5B%22348HK8H3%22%2C%22449H35DA%22%5D%2C%22dateModified%22%3A%222023-01-19T10%3A20%3A59Z%22%7D%7D%5D%7D
Trevisan, R., Trimpey-Warhaftig, R., Gaston, K., Butron, L., Gaballah, S., & Di Giulio, R. T. (2025). Polystyrene nanoplastics impact the bioenergetics of developing zebrafish and limit molecular and physiological adaptive responses to acute temperature stress. Science of The Total Environment, 958, 178026. https://doi.org/10.1016/j.scitotenv.2024.178026 Cite
Trevisan, R., Mello, D. F., Le Gall, A., Corporeau, C., Fabioux, C., Huvet, A., & Paul-Pont, I. (2026). Each temperature degree counts: warming enhances polystyrene nanoplastic toxicity via metabolic disruption in a marine cellular model. Aquatic Toxicology, 291, 107685. https://doi.org/10.1016/j.aquatox.2025.107685 Cite
Penha, L. cristine de carvalho, Hennig, T. B., Nogueira, D. J., Pilotto, M. rangel, Matias, W. gerson, Dafre, A. luiz, & Trevisan, R. (2025). Cytotoxicity of polystyrene nanoplastics involves mitochondrial dysfunction and DNA damage in hemocytes of the Pacific oyster. Ecotoxicology and Environmental Safety, 305, 119245. https://doi.org/10.1016/j.ecoenv.2025.119245 Cite
Carrothers, S., Trevisan, R., Jayasundara, N., Pelletier, N., Weeks, E., Meyer, J. N., Di Giulio, R., & Weinhouse, C. (2025). An epigenetic memory at the CYP1A gene in cancer-resistant, pollution-adapted killifish. SCIENTIFIC REPORTS, 15(1), 3033. https://doi.org/10.1038/s41598-024-82740-w Cite
Gabe, H. B., Taruhn, K. A., Mello, D. F., Lebrun, M., Paillard, C., Corporeau, C., Dafre, A. L., & Trevisan, R. (2025). Prolonged curcumin supplementation causes tissue-specific antioxidant responses in adult oysters: Potential implications for resilience against abiotic and biotic stressors in the aquaculture industry. AQUATIC TOXICOLOGY, 280, 107282. https://doi.org/10.1016/j.aquatox.2025.107282 Cite
Gabe, H. B., Queiroga, F. R., Taruhn, K. A., & Trevisan, R. (2025). Mitigating oxidative stress in oyster larvae: Curcumin promotes enhanced redox balance, antioxidant capacity, development, and resistance to antifouling compounds. AQUATIC TOXICOLOGY, 279, 107231. https://doi.org/10.1016/j.aquatox.2024.107231 Cite
Trevisan, R., & Mello, D. F. (2024). Redox control of antioxidants, metabolism, immunity, and development at the core of stress adaptation of the oyster Crassostrea gigas to the dynamic intertidal environment. FREE RADICAL BIOLOGY AND MEDICINE, 210, 85–106. https://doi.org/10.1016/j.freeradbiomed.2023.11.003 Cite
Dupoue, A., Mello, D. F., Trevisan, R., Dubreuil, C., Queau, I., Petton, S., Huvet, A., Guevel, B., Com, E., Pernet, F., Salin, K., Fleury, E., & Corporeau, C. (2023). Intertidal limits shape covariation between metabolic plasticity, oxidative stress and telomere dynamics in Pacific oyster (Crassostrea gigas). MARINE ENVIRONMENTAL RESEARCH, 191, 106149. https://doi.org/10.1016/j.marenvres.2023.106149 Cite
Trevisan, R., Brander, S. M., & Coffin, S. (2022). Editorial: Microplastics in water and potential impacts on human health. Frontiers in Water, 4, 1101313. https://doi.org/10.3389/frwa.2022.1101313 Cite
