Preventing and mitigating farmed bivalve diseases


Isabelle Arzul, Ifremer, Christine Paillard (WP4)

Project type




Project duration

Start Date

March 1, 2016

End Date

February 29, 2020

The overarching goal of VIVALDI is to increase the sustainability and competitiveness of the European shellfish industry by improving the understanding of bivalve diseases and by developing innovative solutions and tools for the prevention, control and mitigation of the major pathogens affecting the main European farmed shellfish species: Pacific oyster (Crassostrea gigas), mussels (Mytilus edulis and M. galloprovincialis), European flat oyster (Ostrea edulis), clams (Venerupis philippinarum) and scallops (Pecten maximus). The project addresses the most harmful pathogens affecting either one or more of these shellfish species: the virus Ostreid herpesvirus 1 (OsHV-1), Vibrio species including V. aestuarianus, V. splendidus, V. harveyi and V. tapetis, as well as microeukaryotes such as the parasites Perkinsus olseni and Bonamia ostreae.
The project is committed to provide practical solutions based on the most advanced knowledge.
VIVALDI will dissect the disease mechanisms associated with pathogen virulence and pathogenesis and host immune responses, develop in vivo and in vitro models, and apply “omic” approaches that will help the development of diagnostic tools and drugs against pathogen targets, and breeding programmes in a collaborative effort with industrial partners. The proposal will include a global shellfish health approach, recognising that cultured bivalves are often exposed to several pathogens simultaneously, and that disease outbreaks can be due to the combined effect of two or more pathogens. The proposal will also investigate advantages and risks of the used of disease-resistant selected animals in order to improve consumer confidence and safety. VIVALDI will be both multi- and trans-disciplinary. In order to cover both basic and applied levels from molecules to farm, the proposal will integrate partners with a broad range of complementary expertises in pathology and animal health, epidemiology, immunology, molecular biology, genetics, genomics and food safety.


Vivaldi’s study sites

The team


Consortium de 21 partenaires, issus de 10 pays. Les principaux collaborateurs du WP1, WP2 et WP4 :

  • Pierrick Haffray, F. Enez, Syndicat Des Sélectionneurs Avicoles Et Aquacoles Français (SYSAAF), France
  • Lucie Genestou, Labogena Dna, France
  • Sarah Culloty, University College Cork – National University Of Ireland, CORK, Ireland
  • Tovit Lichi, Atlantium Technologies Ltd, Israel
  • Carla Pruzzo, Luigi Vezzulli, Universita Degli Studi Di Genova, Italy
  • Luca Bargelloni, Universita Degli Studi Di Padova, Italy
  • Alberto Pallavicini, Universita Degli Studi Di Trieste, Italy
  • Stein Mortensen, Havforskningsinstituttet, Norway
  • Mathias Wegner, Alfred-Wegener-Institut Helmholtz-Zentrum Fur Polar- Und, Allemagne
  • Lone Madsen Danmarks Tekniske Universitet, Denmark
  • Stephen Feist, David Bass, Nick Taylor, CEFAS, Weymouth, UK
  • Antonio Figueras, Beatriz Novoa, CSIC, Galicia, Spain
  • Dolores Furones, IRTA, Spain