Hélène HEGARET

Physiologie / interactions bivalves/microalgues toxiques

Directrice de recherche
CNRS

Assignment

Laboratoire LEMAR

Equipe/Team PANORAMA

THEMES DE RECHERCHE DÉVELOPPÉS
Culture et physiologie du phytoplancton
Impact du phytoplancton toxique sur la physiologie des bivalves
Ecologie, physiologie, immunité et écotoxicologie des bivalves

RESEARCH THEMS DEVELOPED
Culture, physiology and toxicity of phytoplancton
Impact of toxic phytoplancton on molluscan physiology
Ecology, physiology, immunity and ecotoxicology of molluscs

Contact

helene.hegaret@univ-brest.fr

02 98 49 88 01

Links

Lien vers le CV complet/ link to resume: page 

GdR « PHYCOTOX : Des microalgues aux risques pour l’Homme et l’écosystème» : Groupement de Recherche national GdR3659 CNRS/IFREMER

Scopus Author ID: 6507867020
ORCID ID: 0000-0003-4639-9013
ResearcherID: B-7206-2008
Researchgate page

PROJETS EN COURS : visibles ci-dessous

PUBLICATIONS (2019-2025):

2019

58.  Pousse, E., Flye-Sainte-Marie, J., Alunno-Bruscia, M., Hégaret, H., Rannou, E., Pecquerie, L., Marques, G., Thomas, Y., Castrec, J., Fabioux, C., Long, M., Lassudrie, M., Hermabessière, L., Amzil, Z., Soudant, P., Jean., F. (2018) Modelling paralytic shellfish toxins (PST) accumulation inCrassostrea gigasby using Dynamic Energy Budgets (DEB). Journal of Sea Research. 143:152-164. https://doi.org/10.1016/j.seares.2018.09.002; hal-02114653⟩ (IF2017: 1,729)

  1. Castrec J., Hégaret H., Alunno-Bruscia, M., Picard, M., Soudant P., Petton, B., Boulais, M., Suquet, M., Quéau, I., Ratiskol D., Foulon V., Le Goïc N., Fabioux C. (2019) The dinoflagellate Alexandrium minutum affects development of the oyster Crassostrea gigas, through parental or direct exposure. Environmental Pollution 246: 827-836 (IF2017: 4.348). https://doi.org/10.1016/j.envpol.2018.11.084, ⟨hal-02324570⟩
  2. Long, M., Holland, A., Planquette, H., Santana, D.G., Whitby, H., Soudant, P., Sarthou, G., Hégaret, H., Jolley, D. (2019) A multi-traits approach reveals the effects of Cu on the physiology of a lytic strain of Alexandrium minutum. Aquatic Toxicology 210: 251–261 https://doi.org/10.1016/j.aquatox.2019.03.006, hal-02323399⟩ (IF2017: 4.129)

2020

  1. Gaillard S., Charrier A., Malo F., Carpentier L., Bougaran G., Hégaret H., Réveillon D., Hess P., Séchet V. (2020). Combined effects of temperature, irradiance and pH on Teleaulax amphioxeia (Cryptophycae) physiology and feeding ratio for its predator Mesodinium rubrum (Ciliophora). Journal of Phycology. 56(3):775-783. https://doi.org/10.1111/jpy.12977, hal-02880016)
  2. Castrec, J., Hégaret, H., Huber, M., Le Grand, J., Huvet, A., Tallec, K., Boulais, M., Soudant, P., Fabioux, C. (2020) The toxic dinoflagellate Alexandrium minutum impairs the performance of oyster embryos and larvae. Harmful Algae, 92, 101744 (9p.). https://doi.org/10.1016/j.hal.2020.101744, hal-02879884)
  3. Lassudrie M., Hégaret H., Wikfors GH, da Silva PM (2020) Effects of marine Harmful Algal Blooms on bivalve cellular immunity and infectious diseases: a review. Developmental and Comparative Immunology 108: 103660 https://doi.org/10.1016/j.dci.2020.103660, hal-02880026)
  4. Gaillard S., Le Goïc N., Malo F., Boulais M., Fabioux C., Zaccagnini L., Carpentier L., Sibat M., Réveillon D., Séchet V., Hess P., Hégaret H. (2020). Cultures of Dinophysis sacculus, D. acuminata and pectenotoxin 2 affect gametes and fertilization success of the Pacific oyster, Crassostrea gigas. Env. Poll. 265 (B):114840 10.1016/j.envpol.2020.114840, hal-02880050)

2021

  1. Long, M., Peltekis, A., González-Fernández, C., Hégaret, H., Bailleul, B. (2021) Allelochemicals of Alexandrium minutum: Kinetics of membrane disruption and photosynthesis inhibition in a co-occurring diatom. Harmful Algae, 103:101997. https://doi.org/10.1016/j.hal.2021.101997, ⟨hal-03162016⟩
  2. Gaillard S., Réveillon D., Danthu, C., Hervé, F., Sibat, M., Carpentier L., Hégaret H., Séchet V., Hess P. (2021) Effect of a 24 h salinity stress on the growth, biovolume, toxins, osmolytes and metabolite profiles on three strains of the Dinophysis acuminata-complex (“D. sacculus“) Harmful Algae. 107:102009 https://doi.org/10.1016/j.hal.2021.102009
  3. Castrec, J., Fabioux, C., Le Goïc, N., Boulais, M., Soudant, P., Hégaret, H. (2021). The toxic dinoflagellate Alexandrium minutum affects oyster gamete health and fertilization potential. Marine Environmental research, 169: 105401 https://doi.org/10.1016/j.marenvres.2021.105401
  4. Boullot Floriane, Fabioux Caroline, Hégaret Helene, Boudry Pierre, Soudant Philippe, Benoit Evelyne (2021). Electrophysiological Evaluation of Pacific Oyster (Crassostrea gigas) Sensitivity to Saxitoxin and Tetrodotoxin. Marine Drugs, 19(7), 380 (17p.). https://doi.org/10.3390/md19070380 , https://archimer.ifremer.fr/doc/00704/81561/
  5. Sauvey A., Denis F., Hégaret H., Le Roy B., Lelong C., Jolly O., Pavie M., Fauchot J. (2021) Interactions between filter-feeding bivalves and toxic diatoms: influence on the feeding behavior of Crassostrea gigas and Pecten maximus and on toxin production by Pseudo-nitzschia. Toxins, 13, 577. https://doi.org/10.3390/toxins13080577, ⟨hal-03423356⟩
  6. Faustino, L.S., Queiroga, F.R., Hégaret, H., Marques-Santos, L.F., Neves R.A.F., Nascimento, S. , da Silva, P.M. 2021 Effects of the toxic dinoflagellates Prorocentrum lima and Ostreopsis cf. ovata on immune responses of cultured oysters Crassostrea gasar. Aquatic Toxicology 236 (2021) 105846. https://doi.org/10.1016/j.aquatox.2021.105846

2022

  1. Garcia-Corona, J., Hégaret, H., Deléglise, M., Marzari, A., Rodriguez-Jaramillo, C., Foulon, V., Fabioux,C. 2022 First subcellular localization of the amnesic shellfish toxin, domoic acid, in bivalve tissues: Deciphering the physiological mechanisms involved in its long-retention in the king scallop Pecten Maximus, Harmful Algae, 116 : 102251 (https://doi.org/10.1016/j.hal.2022.102251); ⟨hal-03814644⟩
  2. Even, Y., Pousse, E., Chapperon, C., Artigaud, S., Hégaret, H., Bernay, B., Pichereau, V., Flye-Sainte-Marie, J., Jean, F. 2022 Physiological and comparative proteomic analyzes reveal immune defense response of the king scallop Pecten maximus in presence of paralytic shellfish toxin (PST) from Alexandrium minutum Harmful Algae, 115:102231 (https://doi.org/10.1016/j.hal.2022.102231); (hal-03723474)
  3. Mary, L., Quere, J., Latimier, M., Rovillon, G.A., Hégaret, H., Réveillon, D., Le Gac, M. 2022. Genetic association of toxin production in the dinoflagellate Alexandrium minutum Microbial Genomics 8(11), 000879 (17p.). https://doi.org/10.1099/mgen.0.000879; Open Access version : https://archimer.ifremer.fr/doc/00801/91345/

2023

  1. Gaillard, S., Mason, P.L., Ayache, N., Sanderson, M., Smith, J. L., Giddings, S., McCarron, P., Séchet, V., Hégaret, H., Réveillon, D., Hess, P., Vogelbein, W. K., 2023. Mortality and histopathological of Sheepshead minnow (Cyprinodon variegatus) larvae exposed to pectenotoxin 2 and Dinophysis acuminata. Aquatic Toxicology 257 : 106456 https://doi.org/10.1016/j.aquatox.2023.106456, https://hal.science/hal-04254816
  2. Freire, J.M., Dantas Farias, N., Hégaret, H., da Silva, P.M. 2023. Morphological and functional characterization of the oyster Crassostrea gasar circulating hemocytes: Cell types and phagocytosis activity Fish and Shellfish Immunology Reports 4 (2023) 100089 https://doi.org/10.1016/j.fsirep.2023.100089, https://hal.science/hal-04254779
  3. Long, M., Lelong, A., Soudant, P., Le Grand, F., Bucciarelli, E., Hégaret, H., Physiological adaptation of the diatom Pseudo-nitzschia delicatissima under copper starvation (pre-proofs). Marine Environmental Research https://doi.org/10.1016/j.marenvres.2023.105995
  4. Vanmaldergem, J., García-Corona, J.L., Deléglise, M., Fabioux, C., Hégaret, H. 2023 Effect of the antioxidant N-Acetylcysteine on the depuration of the amnesic shellfish poisoning toxin, domoic acid, in the digestive gland of the king scallop Pecten maximus Aquatic Living Resources 36:14 (https://doi.org/10.1051/alr/2023011), https://hal.univ-brest.fr/hal-04113283

2024

  1. Garcia-Corona, J., Hégaret, H., Lassudrie, M., Derrien, A., Terre-Terrillon, A., Delaire, T., Fabioux,C. 2024. Comparative study of domoic acid accumulation, isomer content and associated digestive subcellular processes in five marine invertebrate species. Aquatic Toxicology 266: 106793 https://doi.org/10.1016/j.aquatox.2023.106793 ⟨hal-04347002⟩
  2. García-Corona, J. L., Fabioux, C., Vanmaldergem, J., Petek, S., Derrien, A., Terre-Terrillon, A., Bressolier Laura, F. Breton & Hegaret, H. (2024). The Amnesic Shellfish Poisoning toxin, domoic acid: the tattoo of the king scallop Pecten maximus. Harmful Algae, 102607. ⟨10.1016/j.hal.2024.102607⟩. ⟨hal-04487905⟩
  3. Queiroga, F.R., Hégaret, H., Carvalho, W.F., Naveira, C., Rodrigues N. Dos Santos, F.S., Silvia Nascimento, S.M., Neves, R.A.F.(2024) In vitro effects of the harmful benthic dinoflagellates Prorocentrum hoffmannianum and Ostreopsis cf. ovata on immune responses of the farmed oyster Crassostrea gasar. Marine Environmental Research, 198, pp.106503. ⟨10.1016/j.marenvres.2024.106503⟩. ⟨hal-04589537⟩
  4. Garcia-Corona, J., Fabioux,C., Hégaret, H. 2024. The queen scallop Aequipecten opercularis: a slow domoic acid depurator? Harmful Algae 138, 102708 https://doi.org/10.1016/j.hal.2024.102708, hal-04682131v1
  5. Le Moan E., Pecquerie L., Régnier-Brisson L., Hégaret H., Lagos P., Heyer L., Lluch-Cota S., Jean F. and Flye-Sainte-Marie J. 2024, Inter-species comparison of life traits relating to amnesic shellfish toxin kinetic in five pectinid species. Ecological Modelling, 499, 110921 (17p.).: https://doi.org/10.1016/j.ecolmodel.2024.110921 , https://archimer.ifremer.fr/doc/00923/103481/
  6. Mary, L., Latimier, M., Serghine, J., Quere, J., Savar, V., Artigaud, S., Réveillon, D., Le Gac, M. Jauzein, C., Hégaret, H., 2025. Alexandrium minutum strains from a recombinant cross show correlated allelopathic activity against the diatom Chaetoceros muelleri and the parasite Amoebophrya sp., independent of PST toxicity. Protist. https://doi.org/10.1016/j.protis.2025.126098, https://archimer.ifremer.fr/doc/00944/105563/, https://hal.univ-brest.fr/hal-05037618v1

2025

  1. Le Moan, E., Derrien, A., Terre-Terrillon, A., Fabioux, C ., Jean F., Lassudrie, M., Flye-Sainte-Marie J.* ; Hégaret H.* (2025) Low contamination and rapid depuration of domoic acid in the variegated scallop, M. varia. Marine Pollution Bulletin 216 : 117946 https://doi.org/10.1016/j.marpolbul.2025.117946, https://archimer.ifremer.fr/doc/00950/106192/        
  2. Bassez, M. Hégaret, H., Maguer, J.F., Legain, M.,  Asquoët, Y., Dulaquais, G. (in rev.)  Domoic acid production by a Pseudo-nitzschia australis strain under zinc and copper exposure. Aquatic Toxicology  Preprint Archimer
  3. Le Moan, E., Derrien, A., Fabioux, C ., Jean F., Lassudrie, M., Terre-Terrillon, A., Flye-Sainte-Marie J.* ; Hégaret H.* (in rev) A 20-years comparative study of domoic acid depuration in king scallops, Pecten maximus, across provinces. Harmful Algae. Preprint : https://www.biorxiv.org/content/10.1101/2025.05.08.652798v1
  4. Queiroga Ramos F., Quéré Le Goïc N., Breton F., Fabioux C., Hégaret H. (in rev) Assessing the effects of three harmful microalgal species on spermatozoa and embryos of the king scallop Pecten maximus. Marine Environmental Research

CHAPITRES d’OUVRAGE (depuis 2019)

  1. Soudant, P. H. Toonen, P.M. da Silva, R. Trombeta, O. Billant, Le Goïc,N., Bidault, A., Lambert, C., Chambouvet, A., Queiroga-Ramos, F., Mendes, A.F ., Bonnin, M., Hégaret, H. Cultiver la mer : enjeux de la conchyliculture dans la planification spatiale marine. Bonnin, Marie (ed.); Bertrand, Sophie (ed.). Planification spatiale marine en Atlantique tropical : d’une tour de Babel à l’organisation d’une intelligence collective, IRD, pp.117-136, 2023, Synthèses, 9782709929721.
  2. Soudant, P. H. Toonen, P.M. da Silva, R. Trombeta, O. Billant, Le Goïc,N., Bidault, A., Lambert, C., Chambouvet, A., Queiroga-Ramos, F., Mendes, A.F ., Bonnin, M., Hégaret, H. Cultivating the sea : Shellfish aquaculture issues in marine spatial planning. Bonnin, Marie (ed.); Bertrand, Sophie (ed.). Marine spatial planning in the tropical Atlantic: from a tower of Babel to collective intelligence, IRD, pp.110-128, 2023, Synthèses, 9782709929721.
  3. Hégaret, H., Mardones, J. 2023 The necessity for bioassays -which ones to select? In GlobalHAB. 2023. Fish-Killing Marine Algal Blooms: Causative Organisms, Ichthyotoxic Mechanisms, Impacts and Mitigation. (eds G.M. Hallegraeff, et al). Paris, UNESCO-IOC/SCOR, 96pp. (IOC Manuals and Guides, 93). 41-45. https://repository.oceanbestpractices.org/handle/11329/2376

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HABIS

HERITAGe

MaSCoET

MICROBIV

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PPP : Preventing Plastic Pollution

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