TY - JOUR TI - Remodeling of the cycling transcriptome of the oyster Crassostrea gigas by the harmful algae Alexandrium minutum AU - Payton, Laura AU - Perrigault, Mickael AU - Hoede, Claire AU - Massabuau, Jean-Charles AU - Sow, Mohamedou AU - Huvet, Arnaud AU - Boullot, Floriane AU - Fabioux, Caroline AU - Hégaret, Hélène AU - Tran, Damien T2 - Scientific Reports AB - As a marine organism, the oyster Crassostrea gigas inhabits a complex biotope governed by interactions between the moon and the sun cycles. We used next-generation sequencing to investigate temporal regulation of oysters under light/dark entrainment and the impact of harmful algal exposure. We found that ≈6% of the gills' transcriptome exhibits circadian expression, characterized by a nocturnal and bimodal pattern. Surprisingly, a higher number of ultradian transcripts were also detected under solely circadian entrainment. The results showed that a bloom of Alexandrium minutum generated a remodeling of the bivalve's temporal structure, characterized by a loss of oscillations, a genesis of de novo oscillating transcripts, and a switch in the period of oscillations. These findings provide unprecedented insights into the diurnal landscape of the oyster's transcriptome and pleiotropic remodeling due to toxic algae exposure, revealing the intrinsic plasticity of the cycling transcriptome in oysters. DA - 2017/06/14/ PY - 2017 DO - 10.1038/s41598-017-03797-4 DP - PubMed VL - 7 IS - 1 SP - 3480 J2 - Sci Rep LA - eng SN - 2045-2322 UR - https://archimer.ifremer.fr/doc/00389/50008/ KW - ACCUTOX_ANR-13-CESA-0019 KW - ACL KW - CNRS KW - Ifremer KW - UBO KW - panorama ER -